267 research outputs found

    Heuristics on pairing-friendly abelian varieties

    Full text link
    We discuss heuristic asymptotic formulae for the number of pairing-friendly abelian varieties over prime fields, generalizing previous work of one of the authors arXiv:math1107.0307Comment: Pages 6-7 rewritten, other minor changes mad

    Explicit CM-theory for level 2-structures on abelian surfaces

    Full text link
    For a complex abelian variety AA with endomorphism ring isomorphic to the maximal order in a quartic CM-field KK, the Igusa invariants j1(A),j2(A),j3(A)j_1(A), j_2(A),j_3(A) generate an abelian extension of the reflex field of KK. In this paper we give an explicit description of the Galois action of the class group of this reflex field on j1(A),j2(A),j3(A)j_1(A),j_2(A),j_3(A). We give a geometric description which can be expressed by maps between various Siegel modular varieties. We can explicitly compute this action for ideals of small norm, and this allows us to improve the CRT method for computing Igusa class polynomials. Furthermore, we find cycles in isogeny graphs for abelian surfaces, thereby implying that the `isogeny volcano' algorithm to compute endomorphism rings of ordinary elliptic curves over finite fields does not have a straightforward generalization to computing endomorphism rings of abelian surfaces over finite fields

    Hazardous Drug Wipe Sampling in Healthcare Facilities

    Get PDF
    Hazardous drugs are associated with causing acute and chronic side effects to healthcare workers that experience occupational exposures. Antineoplastic drugs are known to cause headaches, nausea, vomiting, hair loss, mutagenic activity, spontaneous abortions, infertility, and congenital malformations. Currently, there are no acceptable thresholds for exposures to this type of hazardous drugs. The use of as low as reasonably acceptable (ALARA) is used for exposures to these types of drugs. Occupational exposure risk should be evaluated within facilities where they are used. Performing hazardous drug wipe sampling in areas that are high risk for contamination can provide information to facilities on how to protect their employees

    Hazardous Drug Exposure in Healthcare

    Get PDF
    Hazardous drug exposure in healthcare is a growing concern for the pharma industry and workers. Significant risks may be present including cancers for those handling and compounding various therapeutic agents. Workplace exposure standards do not exist for those employed in the pharma industry. Recommendations of safety have used the, ‘As Low as Reasonably Achievable’ (ALARA) principle to control exposures for pharmacists and others that handle hazardous substances. Steps should be taken to systematically eliminate and/or minimize exposures to workers through safer handling protocols, approved safety cabinets, negative pressure rooms, local exhaust ventilation, health surveillance, training and appropriate PPE

    Association Between Socioeconomic Status Mobility and Inflammation Markers Among White and Black Adults in the United States: A Latent Class Analysis

    Get PDF
    Objective This paper examines whether multidimensional indicators of objective and subjective socioeconomic status (SES) across the life course can be categorized into latent classes of SES mobility and tests the associations of these categories with inflammation markers among White and Black adults. Methods Data are from 592 non-Hispanic White and 158 non-Hispanic Black participants who completed both the baseline survey and biomarkers assessment of the Midlife in the United States (MIDUS) Refresher study. Groups of different SES mobility were examined using latent class analysis. Results White and Black participants showed different patterns of SES mobility. Among Blacks, the latent classes were: 1) Objectively Always High (24.71%; high objective SES across the life course), 2) Subjectively Always High (6.48%; high subjective and low objective SES across the life course), 3) Downwardly Mobile (35.84%; high childhood SES, low adult SES, and 4) Always Low (32.97%; low childhood SES, education, and adult SES). Among Whites, the latent classes were: 1) Always High (52.17%; high childhood SES, high education, high adult SES), 2) Upwardly Mobile (18.14%; low childhood SES, high education, high adult SES), 3) Subjectively Downward (27.74%; high childhood SES, high education, high objective adult SES, low subjective adult SES), and 4) Always Low (1.95%; low childhood SES, education, and adult SES). SES mobility was associated with inflammation in White (Wald χ2’s [3] = 12.89-17.44, p \u3c .050), but not in Black adults (Wald χ2’s [3] = 2.79-7.22, p \u3e .050). Conclusion The lack of SES mobility differentiation on inflammation is an indication of diminished return for the most affluent class among Black participants

    Neighborhood Features and Physiological Risk: An Examination of Allostatic Load

    Get PDF
    Poor neighborhoods may represent a situation of chronic stress, and may therefore be associated with health-related correlates of stress. We examined whether lower neighborhood income would relate to higher allostatic load, or physiological well-being, through psychological, affective, and behavioral pathways. Using data from the Biomarker Project of the Midlife in the United States (MIDUS) study and the 2000 Census, we demonstrated that people living in lower income neighborhoods have higher allostatic load net of individual income. Moreover, findings indicate that this relation is partially accounted for by anxious arousal symptoms, fast food consumption, smoking, and exercise habits

    Switching perspectives: Physicians meet Engineers in a Novel Lab on Medical Device Development

    Full text link
    [EN] Education nowadays often still lacks in seeing the big picture. While becoming an expert in a certain, narrow field is naturally desirable, switching disciplinary perspectives is mandatory for an overall understanding. Next to benefiting from the knowledge of other disciplines itself, the merging of two disciplines and their actors leads to a synergy effect through the exchange of their knowledge and experience. Therefore a mixed course structure consisting of theoretical and practical parts seems most feasible to guarantee varying degrees of didactic approaches including co-operative course designs. In this paper our already well established advanced lab on medical device development (part of the Bachelor's degree in Computer Science) and its enhancement towards an interdisciplinary lab and lecture with medical students is presented. Based on the existing lab, we analyze the prior knowledge of physicians and computer scientists and derive contents, structure and necessary competence goals for a four-week block course. The main objective of the lab is to enable the students of both disciplines to share a common language and a common understanding of the procedures, approaches and tools.Gruenewald, A.; Kroenert, D.; Buechner, S.; Brueck, R. (2019). Switching perspectives: Physicians meet Engineers in a Novel Lab on Medical Device Development. En HEAD'19. 5th International Conference on Higher Education Advances. Editorial Universitat Politècnica de València. 1079-1086. https://doi.org/10.4995/HEAD19.2019.9269OCS1079108

    Perceived Neighborhood Cohesion Buffers COVID-19 Impacts on Mental Health in a United States Sample

    Get PDF
    Objective This study examined whether perceived neighborhood cohesion (the extent to which neighbors trust and count on one another) buffers against the mental health effects of the 2020 COVID-19 pandemic. Methods The XXX University National COVID-19 and Mental Health Study surveyed US adults (N = 3965; M age = 39 years), measuring depressive symptoms, staying home more during than before the 2020 pandemic, and perceived neighborhood cohesion. Results A series of linear regressions indicated that perceiving one\u27s neighborhood as more cohesive was not only associated with fewer depressive symptoms, but also attenuated the relationship between spending more time at home during the pandemic and depressive symptoms. These relationships persisted even after taking into account several individual-level sociodemographic characteristics as well as multiple contextual features, i.e., median household income, population density, and racial/ethnic diversity of the zip codes in which participants resided. Conclusions Neighborhood cohesion may be leveraged to mitigate pandemic impacts on depressive symptoms

    Mapping Urban Performance Culture: A Common Ground for Architecture and Theater

    Full text link
    Our co-taught course focuses on theater history, with an emphasis on performance architecture. Assignments are designed to illuminate the ways in which architectural design and technology inform performance practices and audience reception. The pivotal assignment for exploring interdisciplinarity is a three-week module on mapping historical theaters in New York City. Open-source Global Information Systems (GIS) software serves as a common mechanism for students to situate theatrical productions in the context of the built urban environment, deepening their understanding of the social, economic, and artistic forces that contributed to performance culture. Mapping is a shared pedagogy for analyzing and presenting research findings from different fields. Learning how to collect, analyze, and map data is also a general education skill that can be applied to disciplines across undergraduate curricula
    • …
    corecore